三田和英
教授、博士生导师
国家重要人才计划“外国专家”
中国政府友谊奖获得者（2016）
“外教中国”十大年度人物（2017）
重庆市政府友谊奖获得者（2015）
学习工作经历
1966.4-1970.3: 日本京都大学，学士，高分子化学
1970.4 -1975.3: 日本京都大学，博士，高分子化学，主要从事聚电解质溶液的物理化学研究
1975-1993: 日本国立放射科学研究所研究员，从事染色质结构研究；
1994-2001.3: 日本国立放射科学研究所DNA测序及生物信息学方向负责人，领导fisson酵母的cDNA目录及基因组测序项目。自1997年起，与Maeda博士（加州大学戴维斯分校）及岛田博士（东京大学）启动了家蚕基因项目；
2001.4-2006.3: 日本国立农业生物科学研究所昆虫基因组实验室主任，主持家蚕基因组项目；
2006.4-2008.3: 日本国立农业生物科学研究所昆虫基因组单元负责人，主持家蚕基因组项目；
2008.4-2013.2: 日本国立农业生物科学研究所、特别高级研究员，主持家蚕基因项目及注释项目；
2013.3-至今: 西南大学，国家重要人才计划“外国专家”。
研究领域
家蚕W染色体基因组分析、性别决定级联研究、家蚕家族进化研究、斜纹夜蛾基因组计划等
科学成就
主要从事家蚕W染色体基因组分析、性别决定级联研究、家蚕家族进化研究等。曾任日本国立农业生物科学研究所昆虫基因组实验室主任、特别高级研究员，主持并完成了日本家蚕基因组计划及注释项目，建立了家蚕突变基因定位克隆等。现为西南大学国家重要人才计划特聘外国专家，鉴定完成家蚕所有绒毛膜基因（127个），目前正致力于亚洲重要害虫斜纹夜蛾的国际基因组计划。发表文章200余篇，曾获得日本蚕业科学协会“家蚕基因组分析”特别荣誉（2005）、国际蚕业委员会路易牧场奖（2011）、重庆市友谊奖（2015）、日本贞明皇后纪念蚕业科学技术奖（2015），以及中国政府友谊奖（2016）、“外教中国”十大年度人物（2017）、重庆市政府友谊奖（2015）等。
成果情况
1. Tingcai Cheng, Jiaqi Wu, Yuqian Wu1,etal. ,Marian R. Goldsmith, Qili Feng, Qingyou Xia and Kazuei Mita ，Genomic adaptation to polyphagy and insecticides in a major East Asian noctuid pest，Nature ecology &evolution，Nat Ecol Evol. 2017 DOI: 10.1038/s41559-017-0314-4.
2. Shenglong Li, etal., Qingyou Xia, Kallare P. Arunkumar, and Kazuei Mita1*, A new approach for comprehensively describing heterogametic sex chromosomes, DNA Research, 2018, 0(0), 1–8
3.Mita, K., Ichimura, S., Zama, M. and James, T.C. (1988) Specific codon usage pattern and its implications on the secondary structure of silk fibroin mRNA. J. Mol. Biol. 203, 917-925.
4. Huizhen Guo, etal., Marian R. Goldsmith*, Qingyou Xia, Kazuei Mita*, Expression map of a complete set of gustatory receptor genes in chemosensory organs of Bombyx mori, Insect Biochemistry and Molecular Biolog, 2017, 82(3): 74-82
5. Zhiwei Chen, etal., Marian R. Goldsmith*, Qingyou Xia, Kazuei Mita*, A comprehensive analysis of the chorion locus in silkmoth, Scientific Reports, 2015, 5: 16424
6. Mita, K., etal., T., Goldsmith, M.R. and Maeda, S. (2003) The construction of an EST database for Bombyx mori and its application. Proc. Natl. Acad. Soc. USA 100, 14121-14126.
7. Mita, K., etal., S. and Sasaki, T. (2004) The genome sequence of silkworm, Bombyx mori. DNA Research, 11, 27-35.
8. Mita, K., Ichimura, S., Zama, M. and James, T.C. (1988) Specific codon usage pattern and its implications on the secondary structure of silk fibroin mRNA. J. Mol. Biol. 203, 917-925.
9. Ravikumar Gopalapillai*, Keiko Kadono-Okuda, Kozo Tsuchida+, Kimiko Yamamoto, Junko Nohata, Masahiro Ajimura and Kazuei Mita (2006) Lipophorin receptor from the silkworm, Bombyx mori: cDNA cloning, genomic structure, alternative splicing and isolation of a new isoform. J. Lipid Res. 47, 1005-1013.
10. Yamamoto, K., Narukawa, J., Kadono-Okuda, K., Nohata, J., Sasanuma, M., Suetsugu, Y., Banno, Y., Fujii, H., Goldsmith, M.R. and Mita, K. (2006) Construction of a Single Nucleotide Polymorphism Linkage Map for the Silkworm, Bombyx mori, Based on BAC End-sequences. Genetics 173, 151-161.
11. Ito K, Kidokoro K, Sezutsu H, Nohata J, Yamamoto K, Kobayashi I, Uchino K, Kalyebi A, Eguchi R, Hara W, Tamura T, Katsuma S, Shimada T, Mita K, Kadono-Okuda K. (2008) Deletion of a gene encoding an amino acid transporter in the midgut membrane causes resistance to a Bombyx parvo-like virus. Proc. Natl. Acad. Sci. USA 105: 7523-7527.
12. The International Silkworm Genome Consortium. (2008) The genome of a lepidopteran model insect, the silkworm Bombyx mori. Insect Biochem. Mol. Biol. 38: 1036-1045.
13. Yamamoto K, Nohata J, Kadono-Okuda K, Narukawa J, Sasanuma M, Sasanuma S, Minami H, Shimomura M, Suetsugu Y, Banno Y, Osoegawa K, de Jong P, Goldsmith MR, Mita K. (2008) A BAC-based integrated linkage map of the silkworm, Bombyx mori. Genome Biology 9: R21.
14. Arunkumar, K.P., Mita, K., Nagaraju, J. (2009) Silkworm Z chromosome is enriched in testis-specific genes. Genetics 182: 493-501.
15. Shimomura M, Minami H, Suetsugu Y, Ohyanagi H, Satoh C, Antonio B, Nagamura Y, Kadono-Okuda K, Kajiwara H, Sezutsu H, Nagaraju J, Goldsmith MR, Xia Q, Yamamoto K, Mita K. (2009) KAIKObase: An integrated silkworm genome database and data mining tools. BMC Genomics 10: 486.
16. Liu C, Yamamoto K, Cheng T, Okuda-Kadono K, Narukawa J, Liu S, Han Y, Noda H, Kobayashi I, Futahashi R, Tamura T, Ohnuma A, Banno Y, Dai F, Xiang Z, Goldsmith MR, Mita K, Xia Q. (2010) Repression of tyrosine hydroxylase caused the sex-linked chocolate mutation of the silkworm, Bombyx mori. Proc. Natl. Acad. Sci. USA 107: 12980-12985.
17. Suetsugu Y, Futahashi R, Kanamori H, etal.,, Xia Q, Yamamoto K, Shimada T, Mita K. (2013) Large scale full-length cDNA sequencing reveals a unque genomic landscape in a lepidopteran model insect, Bombyx mori. G3 3:1481-1492.
18. Yamaguchi J, Banno Y, Mita K, Yamamoto K, Ando T, Fujiwara H. (2013) Periodic Wnt1 expression in response to ecdysteroid generates twin-spot markings on caterpillars. Nat Commun 4:1857.
19. Gupta KA, Mita K, Arunkumar KP, Nagaraju J. Molecular architecture of silk fibroin of Indian golden silkmoth, Antheraea assama. Sci Rep. 2015 5:12706 | DOi: 10.1038/srep12706.
20. Chen Z, Nohata J, Guo H, Li S, Liu J, Guo Y, Yamamoto K, Kadono-Okuda K, Liu C, Arunkumar KP, Nagaraju J, Zhang Y, Liu S, Labropoulou V, Swevers L, Tsitoura P, Iatrou K, Gopinathan KP, Goldsmith MR, Xia Q, Mita K. A comprehensive analysis of the chorion locus in silkmoth. Sci Rep. 2015 Nov 10;5:16424. doi: 10.1038/srep16424.
联系方式
Email：mitakazuei@gmail.com