王  菲

     教授、硕士生导师

     教育经历
     2003/9–2008/9，University of Massachusetts Amherst，分子与细胞生物学，博士
     2000/9–2003/7，复旦大学，遗传学，硕士
     1996/9–2000/7，武汉大学，生物学，学士

    工作经历
     2020/7 至今，西南大学，前沿交叉学科研究院生物学研究中心，教授
     2009/10-2020/6，西南大学，家蚕基因组生物学国家重点实验室，副教授
     2018/10-2019/3, University of California San Francisco，Department of Cell and Tissue Biology，访问学者

    研究领域

     以家蚕为模式生物，对先天免疫的分子机理予以解析，侧重于对免疫信号通路中分子间相互作用和调控机制的研究

    成果情况

    代表性论文
    1. Fei Wang. Sending Out Alarms: A Perspective on Intercellular Communications in Insect Antiviral Immune Response. Front. Immunol. 2021, 12:613729
   2. 王鑫怡，肖晓艺，孙畅，王菲*。FADD形成淀粉样蛋白纤维及其在果蝇免疫信号传递中的作用。生物工程学报 2020, 36(6):1198-1208
    3. Jie Hu, Xinyi Wang, Xiaoyi Xiao, Chang Sun, Qingyou Xia, Fei Wang*. A tandem death effector domain-containing protein inhibits the IMD signaling pathway via forming amyloid-like aggregates with the caspase-8 homolog DREDD. Insect Biochem. Mol. Biol. 2019, 114:103225
    4. Fei Wang*, Qingyou Xia. Back to homeostasis: negative regulation of NF-κB immune signaling in insects. Dev. Comp. Immunol. 2018, 87:216-223
    5. Xiaoting Hua, Binbin Li, Liang Song, Cuimei Hu, Xianyang Li, Dandan Wang, Yin Xiong, Ping Zhao, Huawei He*, Qingyou Xia*, Fei Wang*. Stimulator of interferon genes (STING) provides insect antiviral immunity by promoting Dredd caspase-mediated NF-κB activation. J. Biol. Chem. 2018, 293(30):11878-11890
   6. 王菲，李显扬，化晓婷，夏庆友*。家蚕抗BmNPV细胞因子的筛选和分析。中国农业科学 2018, 51(4):789-799
    7. Liang Song#, Fei Wang#, Zhaoming Dong, Xiaoting Hua, Qingyou Xia*. Label-free quantitative phosphoproteomic profiling of cellular response induced by an insect cytokine paralytic peptide. J. Proteomics 2017, 154:49-58
    8. Xiaoting Hua, Xiaojuan Ma, Renju Xue, Tingcai Cheng, Fei Wang*, Qingyou Xia. Characterization of the Bombyx mori Cecropin A1 promoter regulated by IMD pathway. Insect Sci. 2016, 23(2):297-304
    9. Fei Wang, Renju Xue, Xianyang Li, Cuimei Hu, Qingyou Xia*. Characterization of a protein tyrosine phosphatase as a host factor promoting baculovirus replication in silkworm, Bombyx mori. Dev. Comp. Immunol. 2016, 57:31-37
    10. Xiaojuan Ma, Xianyang Li, Shifeng Dong, Qingyou Xia, Fei Wang*. A Fas associated factor negatively regulates anti-bacterial immunity by promoting Relish degradation in Bombyx mori. Insect Biochem. Mol. Biol. 2015, 63:144-151
   11. 王菲，夏庆友*。近现代蚕桑业在美国加利福利亚州的兴衰启示录。蚕业科学 2013, 39(4):0793-0798
    12. Fei Wang#, Cuimei Hu#, Xiaoting Hua, Liang Song, Qingyou Xia*. Translationally Controlled Tumor Protein, a Dual Functional Protein Involved in the Immune Response of the Silkworm, Bombyx mori. PLoS ONE 2013, 8(7), e69284
   13. Fei Wang, Carolyn T.A. Herzig, Chuang Chen, Haoting Hsu, Cynthia L. Baldwin, Janice C. Telfer*. Scavenger receptor WC1 contributes to the γδ T cell response to Leptospira. Mol. Immunol. 2011, 48(6-7):801-809
   14. Wang F, Herzig CT, Dar O, Baldwin CL, Telfer JC*. Tyrosine phosphorylation of scavenger receptor cysteine-rich WC1 is required for the WC1-mediated potentiation of TCR-induced T cell proliferation. Eur. J. Immunol. 2009, 39(1):254-266
   15. Blumerman SL, Wang F, Herzig CT, Baldwin CL*. Molecular cloning of bovine chemokines receptors and expression by WC1+ gamma-delta T cells. Dev. Comp. Immunol. 2007, 31(1):87-102
   16. Qi Q#, Wang F#, Zhang H, Wang J, Xiao H, Wang M, Han Y, Zhang R, Tao S, Luo Z*. Induced recovery of defective membrane expression of a CC chemokine receptor 5 mutant by phytohemagglutinin. Cell. Mol. Life. Sci. 2003, 60:2492-2500

   译著
   现代生物学发展史——从西番莲到肿瘤鼠。Jim Endersby 著，王菲 译。科学出版社，2021年6月

     联系方式

     Email：fwangswu@gmail.com