钱文良
个人简介
理学博士，副教授，硕士生导师。重庆市巴渝青年学者，重庆市青年创新人才。中国昆虫学会昆虫生理生化与分子生物学专业委员会青年委员，重庆市昆虫学会常务理事，重庆市昆虫学会昆虫生理生化与分子生物学专业委员会副主任，重庆市昆虫学会发育与遗传专委会委员。主持国家自然科学基金、重庆市自然科学基金、中国博士后科学基金等项目。以第一作者或通讯作者在Science Advances、PNAS、Nucleic Acids Res、Cell Rep、PLoS Genet、J Biol Chem、Insect Biochem Mol Biol、Insect Sci等杂志发表学术论文。参编专著1部。获重庆市自然科学二等奖，获重庆市优秀博士学位论文。
学习工作经历
2020.07-至今 西南大学生物学研究中心，副教授
2024.07-2025.06 加州大学河滨分校，项目科学家
2018.01-2020.06 西南大学博士后
2012.07-2017.12 西南大学硕博连读，理学博士
2008.09-2012.06 吉林农业大学，工学学士
研究领域
主要以家蚕丝腺和果蝇唾液腺为研究模型，解析器官生长发育和细胞核内复制的分子调控机理，阐明丝蛋白合成的调控网络。
近5年代表性论文：
(1) Wenliang Qian#*; Xing Zhang#; Dongqin Yuan#; Yuting Wu; Hao Li; Ling Wei; Zheng Li; Zongcai Dai; Pei Song; Qiaoling Sun; Zizhang Zhou; Qingyou Xia; Daojun Cheng*; USP8 and Hsp70 regulate endoreplication by synergistically promoting Fzr deubiquitination and stabilization, Science Advances, 2025, 11(12): eadq9111.
(2) Wenliang Qian#; Zheng Li#; Wei Song; Tujing Zhao; Weina Wang; Jian Peng; Ling Wei; Qingyou Xia; Daojun Cheng*; A novel transcriptional cascade is involved in Fzr-mediated endoreplication, Nucleic Acids Research, 2020, 48(8): 4214-4229.
(3) Wenliang Qian#*; Hao Li#; Xing Zhang; Yaohao Tang; Dongqin Yuan; Zhu Huang; Daojun Cheng*; Fzr regulates silk gland growth by promoting endoreplication and protein synthesis in the silkworm, PLoS Genetics, 2023, 19(1): e1010602.
(4) Dongqin Yuan; Xing Zhang; Yan Yang; Ling Wei; Hao Li; Tujing Zhao; Mengge Guo; Zheng Li; Zhu Huang; Min Wang; Zongcai Dai; Peixin Li; Qingyou Xia; Wenliang Qian*; Daojun Cheng*; Schlank orchestrates insect developmental transition by switching H3K27 acetylation to trimethylation in the prothoracic gland, Proceedings of the National Academy of Sciences of the United States of America, 2024, 121(35): e2401861121.
(5) Zheng Li; Wenliang Qian#; Wei Song; Tujing Zhao; Yan Yang; Weina Wang; Ling Wei; Dongchao Zhao; Yaoyao Li; Norbert Perrimon; Qingyou Xia; Daojun Cheng; A salivary gland-secreted peptide regulates insect systemic growth, Cell Reports, 2022, 38(8): 110397.
(6) Wenliang Qian#; Mengge Guo#; Jian Peng#; Tujing Zhao; Zheng Li; Yan Yang; Hao Li; Xing Zhang; Kirst King-Jones*; Daojun Cheng*; Decapentaplegic retards lipolysis during metamorphosis in Bombyx mori and Drosophila melanogaster, Insect Biochemistry and Molecular Biology, 2023, 155: 103928.
(7) Wenliang Qian; Yan Yang; Zheng Li; Yuting Wu; Xuechuan He; Hao Li; Daojun Cheng*;
Enhanced Myc expression in silkworm silk gland promotes DNA replication and silk production, Insects, 2021, 12(4): 361-368.
(8) Wenliang Qian; Xiaoxu Gang; Tianlei Zhang; Ling Wei; Xinxin Yang; Zheng Li; Yan Yang; Liang Song; Peng Wang; Jian Peng; Daojun Cheng*; Qingyou Xia*; Protein kinase A-mediated phosphorylation of the Broad-Complex transcription factor in silkworm suppresses its transcriptional activity, Journal of Biological Chemistry, 2017, 292(30): 12460-12470.
(8) Wenliang Qian; Lixia Kang; Tianlei Zhang; Meng Meng; Yonghu Wang; Zhiqing Li; Qingyou Xia*; Daojun Cheng*; Ecdysone receptor (EcR) is involved in the transcription of cell cycle genes in the silkworm, International Journal of Molecular Sciences, 2015, 16(2): 3335-3349.
(9) Mengpei Guo#; Wenliang Qian#; Xuechuan He; Jian Peng; Peng Wang; Weina Wang; Qingyou Xia; Daojun Cheng*; Genome-wide identification of target genes for transcription factor BR-C in the silkworm, Bombyx mori, Insect Science, 2021, 28(6): 1530-1540.
(10) Yaohao Tang#; Xing Zhang#; Zongcai Dai; Hao Li; Yan Yang; Tujing Zhao; Dongqin Yuan; Wenliang Qian*; Daojun Cheng*; CRISPR-Cas13-mediated RNA editing in the silkworm Bombyx mori, Zoological Research, 2024, 45(6): 1249-1260.
联系方式：
Email：qianwl@swu.edu.cn